eGFR Calculator
Download calculator to your personal device. Use calculator in conjunction with our eGFR Summary Card for CKD Management in General Practice
* Calculator layout may vary depending on implementation of Java on each mobile device
Due to varying implementation of Java
** unzip and copy files to mobile device
*** download directly to mobile device, need both files
(NB: you may need to "right-click" and select Save as for the JAD file
Ms Chris Archibald | KCAT Project Manager | GPO Box 9993 Adelaide SA 5001
eGFR Clinical Tools
Clinical situations where the eGFR (estimated Glomerular Filtration Rate) results may be unreliable and/or misleading include:
- Clinical situations where eGFR results may be unreliable and/or misleading include:
- Acute changes in kidney function (eg. acute kidney failure)
- Dialysis-dependent patients
- Exceptional dietary intake (e.g. vegetarian diet, high protein diet, recent consumption of cooked meat, creatine supplements)
- Extremes of body size
- Diseases of skeletal muscle, paraplegia, or amputees (may underestimate) or high muscle mass (may overestimate)
- Children under the age of 18 years
- Severe liver disease present
The original MDRD formula (see calculator above) contains a factor to be applied to African-American subjects raising the possibility that other variations in the formula may be required for optimal performance in different racial groups.
Use of eGFR in different ethnic populations
Pending publication of validation studies it is recommended, Australasian laboratories continue to automatically report eGFR in Aboriginal and Torres Strait Islander peoples and other ethnic groups. For critical dose drugs, particularly in the hospital setting, it remains important to adhere to the published recommendations.
eGFR and drug dosing
Where an eGFR result (using MDRD) is presented it is clinically appropriate to use this to assist drug dosing decision making. Published recommendations usually involve the use of the Cockcroft-Gault equation to estimate eGFR, or to measure creatinine clearance in order to amend dosing for renal function. Cockcroft-Gault GFR formula may still be used for drug dosing calculation.
Refer to the eGFR Position Statement and our Patient Fact Sheet explaining eGFR estimated Glomerular Filtration Rate (Know your number) for more information.
Chronic Kidney Disease (CKD) Management in General Practice - Educational booklet for Health Professionals
The Chronic Kidney Disease (CKD) Management in General Practice booklet (and supporting Publication reference List) has been formally endorsed by the RACGP and ANZSN and Kidney Health Australia and published by us to provide a comprehensive summary of current guidelines and recommendations from various sources on the management of CKD in general practice. This booklet has been written for health professionals involved in the care and treatment of people with kidney disease. It is accompanied by a laminated Summary Card for CKD Management in General Practice.
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eGFR
mL/min/1.73m2
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Description
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Clinical Action Plan
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≥ 90
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Stage 1 CKD
- kidney damage* with normal kidney function
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Further investigation for CKD may be indicated in those at increased risk**:
- blood pressure
- assessment of proteinuria
- urinalysis
Cardiovascular risk reduction:
- blood pressure
- lipids
- blood glucose
- lifestyle modification (smoking, weight, physical activity, nutrition, alcohol)
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60-89
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Stage 2 CKD
- kidney damage* with mild kidney function
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30 - 59
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Stage 3 CKD
- moderate kidney function
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As above, plus:
- monitor eGFR 3 monthly
- avoid nephrotoxic drugs
- prescribe antiproteinuric drugs (ACE inhibitors and/or ARBs) if appropriate
- address common complications
- ensure drug dosages appropriate for level of kidney function
Consider indications for referral to a nephrologist
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15 - 29
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Stage 4 CKD
- severe kidney function
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As above + referral to nephrologist is usually indicated for physical and psychosocial preparation for renal replacement therapy (dialysis, pre-emptive transplantation, transplantation) or conservative medical management
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< 15
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Stage 5 CKD
- end-stage kidney disease
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As above + referral to a nephrologist
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* imaging or biopsy abnormalities, or proteinuria/haematuria
** hypertension, diabetes, smoker, age > 50 yrs, obesity, family history of kidney disease, Aboriginal and Torres Strait Islander people |